During a median 8.7 years of follow-up, there were 1806 deaths, including 777 from CVD. Results In cross-sectional multivariate analyses, increasing age, female sex, nonwhite race/ethnicity, diabetes, current smoking, and higher body mass index were all independently associated with higher odds of 25(OH)D deficiency (lowest quartile of 25(OH)D level, <17.8 ng/mL ), while greater physical activity, vitamin D supplementation, and nonwinter season were inversely associated. Participant vitamin D levels were collected from 1988 through 1994, and individuals were passively followed for mortality through 2000. Methods We tested the association of low 25(OH)D levels with all-cause, cancer, and cardiovascular disease (CVD) mortality in 13 331 nationally representative adults 20 years or older from the Third National Health and Nutrition Examination Survey (NHANES III) linked mortality files. However, whether low serum 25(OH)D levels are associated with mortality in the general population is unknown. Observational data suggests that low 25-hydroxyvitamin D levels (25D) are associated with diabetes mellitus, hypertension, and cancers.
Shared Decision Making and Communicationīackground In patients undergoing dialysis, therapy with calcitriol or paricalcitol or other vitamin D agents is associated with reduced mortality.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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